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  • Suspicious Powder Episodes and the ED

    The next time you are in the ED and have a quiet moment, review your hazardous material protocols. Imagine a scenario where, by terror attack, terror hoax, or public fear, an asymptomatic individual (or individuals) brings to you a suspicious powder or substance. Is there a rational approach to handling this situation?
  • ECG Review: What’s Going On? (Part II)

    The 12-lead ECG and accompanying rhythm strip in the Figure were obtained from an 84-year-old man who presented to the emergency department with acute dyspnea from pneumonia and heart failure. Can you account for the relatively slow heart rate despite his acute shortness of breath?
  • Trends in clinical research require updated policies on tissue banking

    Researchers and clinical trials managers may have noticed that the best practices standards in tissue banking have been evolving in recent years due to scientific advances, greater public scrutiny on human subject protection, and new privacy rules under the Health Insurance Portability and Accountability Act.
  • Research on the dead: Standards are required

    A cardiovascular surgeon develops an experimental intravascular blood oxygenation device that has the potential to eliminate the need for mechanical ventilation in severely injured patients. However, testing the device in human patients would be unethical because of the great risk of harm, and the still-unknown chance for benefit.
  • News Briefs

    Smallpox vaccine draft guidance issued by FDA; New technology, lack of consent leads to lawsuit
  • Full March 1, 2004 Issue in PDF

  • Blood substitute study raises consent questions

    In emergency medicine and critical care, clinical trials are difficult to conduct. The unpredictable and time-sensitive nature of these specialties means that controlled, randomized, clinical trials are difficult, sometimes impossible to design.
  • A few simple rules ensure data sharing compliance

    The National Institutes of Health (NIH) wants all research supported with NIH funds to be shared with other investigators and made available to the public, but how can this philosophy be reconciled with privacy laws and concerns?
  • Clinical Briefs in Primary Care

    Risk of Adenocarcinoma in Barretts Esophagus; Long-Term Effect of Doxazosin, Finasteride, and Combination for BPH; Once Daily Valacyclovir to Reduce Herpes Transmission; Use of B-Type Natriuretic Peptide in the Evaluation and Management of Acute Dyspnea; Association Between C-reactive Protein and Age-related Macular Degeneration; VZV Reactivation in Astronauts
  • Full April 2004 Issue in PDF